Structure of PDB 3tq1 Chain A Binding Site BS01

Receptor Information
>3tq1 Chain A (length=423) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MATGQDRVVALVDMDCFFVQVEQRQNPHLRNKPCAVVQYKSWKGGGIIAV
SYEARAFGVTRSMWADDAKKLCPDLLLAQVRESRGKANLTKYREASVEVM
EIMSRFAVIERASIDEAYVDLTSAVQERLQKLQGQPISADLLPSTYIEGL
PQGTVQKEGMRKQGLFQWLDSLQIDNLTSPDLQLTVGAVIVEEMRAAIER
ETGFQCSAGISHNKVLAKLACGLNKPNRQTLVSHGSVPQLFSQMPIRKIR
SLGGKLGASVIEILGIEYMGELTQFTESQLQSHFGEKNGSWLYAMCRGIE
HDPVKPRQLPKTIGCSKNFPGKTALATREQVQWWLLQLAQELEERLTKDR
NDNDRVATQLVVSIRVQGDKRLSSLRRCCALTRYDAHKMSHDAFTVIKNM
NTSTEWSPPLTMLFLCATKFSAS
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB3tq1 Human DNA Polymerase Eta Is Pre-Aligned for dNTP Binding and Catalysis.
Resolution2.556 Å
Binding residue
(original residue number in PDB)		Q38 Y39 W42 K86 R93 P316 K317 G320 S322 K323 N324 R351
Binding residue
(residue number reindexed from 1)		Q38 Y39 W42 K86 R93 P310 K311 G314 S316 K317 N318 R345
Enzymatic activity
Enzyme Commision number 2.7.7.7: DNA-directed DNA polymerase.
Gene Ontology
Molecular Function
GO:0003684 damaged DNA binding
Biological Process
GO:0006281 DNA repair

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Molecular Function
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Biological Process
External links
PDB RCSB:3tq1, PDBe:3tq1, PDBj:3tq1
PDBsum3tq1
PubMed22154937
UniProtQ9Y253|POLH_HUMAN DNA polymerase eta (Gene Name=POLH)

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