Structure of PDB 3tpm Chain A Binding Site BS01
Receptor Information
>3tpm Chain A (length=422) Species:
10090
(Mus musculus) [
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NWSVEDIVKGINSNNLESQLQATQAARKLLSREKQPPIDNIIRAGLIPKF
VSFLGKTDCSPIQFESAWALTNIASGTSEQTKAVVDGGAIPAFISLLASP
HAHISEQAVWALGNIAGDGSAFRDLVIKHGAIDPLLALLAVPDLSTLACG
YLRNLTWTLSNLCRNKNPAPPLDAVEQILPTLVRLLHHNDPEVLADSCWA
ISYLTDGPNERIEMVVKKGVVPQLVKLLGATELPIVTPALRAIGNIVTGT
DEQTQKVIDAGALAVFPSLLTNPKTNIQKEATWTMSNITAGRQDQIQQVV
NHGLVPFLVGVLSKADFKTQKEAAWAITNYTSGGTVEQIVYLVHCGIIEP
LMNLLSAKDTKIIQVILDAISNIFQAAEKLGETEKLSIMIEECGGLDKIE
ALQRHENESVYKASLNLIEKYF
Ligand information
>3tpm Chain B (length=14) Species:
10090
(Mus musculus) [
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LKRKLKLKRARLAD
Receptor-Ligand Complex Structure
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PDB
3tpm
Sensing actin dynamics: structural basis for G-actin-sensitive nuclear import of MAL
Resolution
2.1 Å
Binding residue
(original residue number in PDB)
S105 F138 W142 N146 S149 G150 T155 Q181 W184 N188 G191 D192 N228 W231 R238 D270 W273 V321 T322 T328 W357 N361 E396 W399
Binding residue
(residue number reindexed from 1)
S31 F64 W68 N72 S75 G76 T81 Q107 W110 N114 G117 D118 N154 W157 R164 D196 W199 V247 T248 T254 W283 N287 E322 W325
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:3tpm
,
PDBe:3tpm
,
PDBj:3tpm
PDBsum
3tpm
PubMed
21964294
UniProt
P52293
|IMA1_MOUSE Importin subunit alpha-1 (Gene Name=Kpna2)
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