Structure of PDB 3to6 Chain A Binding Site BS01

Receptor Information
>3to6 Chain A (length=276) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
EVARVRNLNRIIMGKYEIEPWYFSPYPIELTDEDFIYIDDFTLQYFGSKK
QYERYRKKCTLRHPPGNEIYRDDYVSFFEIDGRKQRTWCRNLCLLSKLFL
DHKTLYYDVDPFLFYCMTRRDELGHHLVGYFSKEKESADGYNVACILTLP
QYQRMGYGKLLIEFSYELSKKENKVGSPEKPLSDLGLLSYRAYWSDTLIT
LLVEHQKEITIDEISSMTSMTTTDILHTAKTLNILRYYKGQHIIFLNEDI
LDRYNRLKAKKRRTIDPNRLIWKPPV
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB3to6 MYST protein acetyltransferase activity requires active site lysine autoacetylation.
Resolution2.1 Å
Binding residue
(original residue number in PDB)		L259 K262 T263 A303 C304
Binding residue
(residue number reindexed from 1)		L100 K103 T104 A144 C145
Enzymatic activity
Catalytic site (original residue number in PDB) C304 E338
Catalytic site (residue number reindexed from 1) C145 E179
Enzyme Commision number 2.3.1.-
2.3.1.48: histone acetyltransferase.
Gene Ontology
Molecular Function
GO:0004402 histone acetyltransferase activity
Biological Process
GO:0006355 regulation of DNA-templated transcription

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Molecular Function
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Biological Process
External links
PDB RCSB:3to6, PDBe:3to6, PDBj:3to6
PDBsum3to6
PubMed22020126
UniProtQ08649|ESA1_YEAST Histone acetyltransferase ESA1 (Gene Name=ESA1)

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