Structure of PDB 3tl0 Chain A Binding Site BS01
Receptor Information
>3tl0 Chain A (length=99) Species:
9606
(Homo sapiens) [
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RWFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHI
KIQNTGDYYDLYGGEKFATLAELVQYYMEHHGQLKEKNGDVIELKYPLN
Ligand information
>3tl0 Chain B (length=7) [
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LNYAQLW
Receptor-Ligand Complex Structure
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PDB
3tl0
Simultaneous binding of two peptidyl ligands by a SRC homology 2 domain.
Resolution
2.05 Å
Binding residue
(original residue number in PDB)
G13 E17 R32 S34 K35 S36 T52 H53 K55 K89 E90 K91
Binding residue
(residue number reindexed from 1)
G9 E13 R28 S30 K31 S32 T48 H49 K51 K85 E86 K87
Enzymatic activity
Enzyme Commision number
3.1.3.48
: protein-tyrosine-phosphatase.
External links
PDB
RCSB:3tl0
,
PDBe:3tl0
,
PDBj:3tl0
PDBsum
3tl0
PubMed
21800896
UniProt
Q06124
|PTN11_HUMAN Tyrosine-protein phosphatase non-receptor type 11 (Gene Name=PTPN11)
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