Structure of PDB 3tj9 Chain A Binding Site BS01

Receptor Information
>3tj9 Chain A (length=155) Species: 210 (Helicobacter pylori) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MIIERLVGNLRDLNPLDFSVDYVDLEWFETRKKIARFKTRQGKDIAIRLK
DAPKLGLSQGDILFKEEKEIIAVNILDSEVIHIQAKSVAEVAKICYEIGN
RHAALYYGESQFEFKTPFEKPTLALLEKLGVQNRVLSSKLDSKERLTVSM
PHSEP
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain3tj9 Chain A Residue 171 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB3tj9 Crystallographic and X-ray absorption spectroscopic characterization of Helicobacter pylori UreE bound to Ni2+ and Zn2+ reveals a role for the disordered C-terminal arm in metal trafficking.
Resolution2.521 Å
Binding residue
(original residue number in PDB)		H102 E154
Binding residue
(residue number reindexed from 1)		H102 E154
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005515 protein binding
GO:0016151 nickel cation binding
GO:0051082 unfolded protein binding
Biological Process
GO:0006457 protein folding
GO:0019627 urea metabolic process
GO:0065003 protein-containing complex assembly
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:3tj9, PDBe:3tj9, PDBj:3tj9
PDBsum3tj9
PubMed22010876
UniProtQ09064|UREE_HELPY Urease accessory protein UreE (Gene Name=ureE)

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