Structure of PDB 3tiw Chain A Binding Site BS01
Receptor Information
>3tiw Chain A (length=160) Species:
9606
(Homo sapiens) [
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RPNRLIVDEAINEDNSVVSLSQPKMDELQLFRGDTVLLKGKKRREAVCIV
LSDDTCSDEKIRMNRVVRNNLRVRLGDVISIQPCPDVKYGKRIHVLPIDD
TGNLFEVYLKPYFLEAYRPIRKGDIFLVRGGMRAVEFKVVETDPSPYCIV
APDTVIHCEG
Ligand information
>3tiw Chain C (length=18) Species:
9606
(Homo sapiens) [
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VTLRRRMLAAAAERRLQK
Receptor-Ligand Complex Structure
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PDB
3tiw
The Structural and Functional Basis of the p97/Valosin-containing Protein (VCP)-interacting Motif (VIM): MUTUALLY EXCLUSIVE BINDING OF COFACTORS TO THE N-TERMINAL DOMAIN OF p97.
Resolution
1.802 Å
Binding residue
(original residue number in PDB)
D35 F52 R53 G54 I70 V108 Y110 A142 Y143 R144 I175
Binding residue
(residue number reindexed from 1)
D14 F31 R32 G33 I49 V87 Y89 A116 Y117 R118 I149
Enzymatic activity
Enzyme Commision number
3.6.4.6
: vesicle-fusing ATPase.
External links
PDB
RCSB:3tiw
,
PDBe:3tiw
,
PDBj:3tiw
PDBsum
3tiw
PubMed
21914798
UniProt
P55072
|TERA_HUMAN Transitional endoplasmic reticulum ATPase (Gene Name=VCP)
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