Structure of PDB 3tfm Chain A Binding Site BS01

Receptor Information
>3tfm Chain A (length=208) Species: 10116 (Rattus norvegicus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PYFHSFLYMNGGLMNSWKRRWCVLKDETFLWFRSKQEALKQGWLHNNGGG
SSTLSRRNWKKRWFVLRQSKLMYFENDSEEKLKGTVEVRSAKEIIDNTNK
ENGIDIIMADRTFHLIAESPEDASQWFSVLSQVHSSTDQEIREMHDEQAN
PQNAVGTLDVGLIDSVCASDSPDRPNSFVIITANRVLHCNADTPEEMHHW
ITLLQRSK
Ligand information
Ligand IDPO4
InChIInChI=1S/H3O4P/c1-5(2,3)4/h(H3,1,2,3,4)/p-3
InChIKeyNBIIXXVUZAFLBC-UHFFFAOYSA-K
SMILES
SoftwareSMILES
CACTVS 3.341[O-][P]([O-])([O-])=O
ACDLabs 10.04[O-]P([O-])([O-])=O
OpenEye OEToolkits 1.5.0[O-]P(=O)([O-])[O-]
FormulaO4 P
NamePHOSPHATE ION
ChEMBL
DrugBankDB14523
ZINC
PDB chain3tfm Chain A Residue 217 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB3tfm Structural basis of the myosin X PH1N-PH2-PH1C tandem as a specific and acute cellular PI(3,4,5)P3 sensor
Resolution2.53 Å
Binding residue
(original residue number in PDB)		R28 R41
Binding residue
(residue number reindexed from 1)		R20 R33
Annotation score3
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:3tfm, PDBe:3tfm, PDBj:3tfm
PDBsum3tfm
PubMed21965296
UniProtD3ZJP6|MYO10_RAT Unconventional myosin-X (Gene Name=Myo10)

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