Structure of PDB 3tfc Chain A Binding Site BS01

Receptor Information

>3tfc Chain A (length=343) Species: 169963 (Listeria monocytogenes EGD-e) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

LRTQVDQLNIDLLELISKRANLVQEIGKIKLRFDPLREREMLNTILAANE
GPFEDSTVQKLFKEIFKAGLELQEEDHSKALLVSRKNKKEDTIVTVKGLP
IGNGEPVFVFGPCSVESYEQVAAVAESIKAKGLKLIRGGAFKPRTSPYDF
QGLGLEGLKILKRVSDEYGLGVISEIVTPADIEVALDYVDVIQIGARNMQ
NFELLKAAGRVDKPILLKRGLSATIEEFIGAAEYIMSQGNGKIILCERGI
RTYEKATRNTLDISAVPILKKETHLPVMVDVTHSTGRKDLLLPCAKAALA
IEADGVMAEVHPDPAVALSDSAQQMDIPEFEEFWNAILASNLV

Ligand information

Ligand ID

InChI

InChI=1S/Mn/q+2

InChIKey

WAEMQWOKJMHJLA-UHFFFAOYSA-N

SMILES

Software	SMILES
ACDLabs 10.04 OpenEye OEToolkits 1.5.0	[Mn+2]
CACTVS 3.341	[Mn++]

Formula

Name

MANGANESE (II) ION

PDB chain

3tfc Chain A Residue 362 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

Global view

Local view

Structure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]

PDB	3tfc Structural analysis of a 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase with an N-terminal chorismate mutase-like regulatory domain.
Resolution	1.95 Å
Binding residue (original residue number in PDB)	C126 H296 E322 D333
Binding residue (residue number reindexed from 1)	C113 H283 E309 D320
Annotation score	4

Enzymatic activity

Enzyme Commision number

Gene Ontology

	Molecular Function
GO:0016832	aldehyde-lyase activity
GO:0046872	metal ion binding

	Biological Process
GO:0009058	biosynthetic process
GO:0009073	aromatic amino acid family biosynthetic process
GO:0046417	chorismate metabolic process

View graph for
Molecular Function

View graph for
Biological Process

External links

PDB	RCSB:3tfc, PDBe:3tfc, PDBj:3tfc
PDBsum	3tfc
PubMed	22505283
UniProt	Q8Y6T2

[Back to BioLiP]