Structure of PDB 3tcg Chain A Binding Site BS01

Receptor Information
>3tcg Chain A (length=517) Species: 83333 (Escherichia coli K-12) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ADVPAGVTLAEKQTLVRNNGSEVQSLDPHKIEGVPESNISRDLFEGLLVS
DLDGHPAPGVAESWDNKDAKVWTFHLRKDAKWSDGTPVTAQDFVYSWQRS
VDPNTASPYASYLQYGHIAGIDEILEGKKPITDLGVKAIDDHTLEVTLSE
PVPYFYKLLVHPSTSPVPKAAIEKFGEKWTQPGNIVTNGAYTLKDWVVNE
RIVLERSPTYWNNAKTVINQVTYLPIASEVTDVNRYRSGEIDMTNNSMPI
ELFQKLKKEIPDEVHVDPYLCTYYYEINNQKPPFNDVRVRTALKLGMDRD
IIVNKVKAQGNMPAYGYTPPYTDGAKLTQPEWFGWSQEKRNEEAKKLLAE
AGYTADKPLTINLLYNTSDLHKKLAIAASSLWKKNIGVNVKLVNQEWKTF
LDTRHQGTFDVARAGWCADYNEPTSFLNTMLSNSSMNTAHYKSPAFDSIM
AETLKVTDEAQRTALYTKAEQQLDKDSAIVPVYYYVNARLVKPWVGGYTG
KDPLDNTYTRNMYIVKH
Ligand information
Receptor-Ligand Complex Structure
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PDB3tcg Escherichia coli peptide binding protein OppA has a preference for positively charged peptides.
Resolution2.0 Å
Binding residue
(original residue number in PDB)		E58 G59 V60 Y135 W423 G441 W442 C443 D445 Y511
Binding residue
(residue number reindexed from 1)		E32 G33 V34 Y109 W397 G415 W416 C417 D419 Y485
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:1900750 oligopeptide binding
GO:1904680 peptide transmembrane transporter activity
Biological Process
GO:0006857 oligopeptide transport
GO:0009408 response to heat
GO:0015031 protein transport
GO:0015833 peptide transport
GO:0055085 transmembrane transport
GO:0061077 chaperone-mediated protein folding
GO:0140205 oligopeptide import across plasma membrane
Cellular Component
GO:0016020 membrane
GO:0030288 outer membrane-bounded periplasmic space
GO:0042597 periplasmic space
GO:0043190 ATP-binding cassette (ABC) transporter complex
GO:0055052 ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:3tcg, PDBe:3tcg, PDBj:3tcg
PDBsum3tcg
PubMed21983341
UniProtP23843|OPPA_ECOLI Periplasmic oligopeptide-binding protein OppA (Gene Name=oppA)

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