Structure of PDB 3stj Chain A Binding Site BS01

Receptor Information

>3stj Chain A (length=300) Species: 83333 (Escherichia coli K-12)

PLPSLAPMLEKVLPAVVSVRVEGTQPFEGLGSGVIINASKGYVLTNNHVI
NQAQKISIQLNDGREFDAKLIGSDDQSDIALLQIQNPSKLTQIAIADSDK
LRVGDFAVAVGNPFGLGQTATSGIVSALGRSGLNLEGLENFIQTDASINR
GNSGGALLNLNGELIGINTAILAPGGGSVGIGFAIPSNMARTLAQQLIDF
GEIKRGLLGIKGTEMSADIAKAFNLDVQRGAFVSEVLPGSGSAKAGVKAG
DIITSLNGKPLNSFAELRSRIATTEPGTKVKLGLLRNGKPLEVEVTLDTS

Ligand information

>3stj Chain M (length=5) Species: 562 (Escherichia coli)

AAAAA

Receptor-Ligand Complex Structure

Structure summary

• PDB: 3stj Molecular adaptation of the DegQ protease to exert protein quality control in the bacterial cell envelope.
• Resolution: 2.6 Å
• Binding residue (original residue number in PDB): L241 L242 I244 G246 F298
• Binding residue (residue number reindexed from 1): L207 L208 I210 G212 F264

Enzymatic activity

• Enzyme Commision number: 3.4.21.107: peptidase Do.

Gene Ontology

Molecular Function

• GO:0004252 serine-type endopeptidase activity

Biological Process

• GO:0006508 proteolysis

External links

• PDB: RCSB:3stj, PDBe:3stj, PDBj:3stj
• PDBsum: 3stj
• PubMed: 21685389
• UniProt: P39099|DEGQ_ECOLI Periplasmic pH-dependent serine endoprotease DegQ (Gene Name=degQ)