Structure of PDB 3sri Chain A Binding Site BS01

Receptor Information
>3sri Chain A (length=286) Species: 5835 (Plasmodium falciparum CAMP/Malaysia) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
NPWTEYMAKYDIEEVHGSGIRVDLGEDAEVAGTQYRLPSGKCPVFGKGII
IENSKTTFLKPVATGNQDLKDGGFAFPPTEPLISPMTLNGMRDFYKNNEY
VKNLDELTLCSRHAGNMNPDKDENSNYKYPAVYDDKDKKCHILYIAAQEN
NGPMFCFRPAKDKSFQNYVYLSKNVVDNWEKVCPRKNLENAKFGLWVDGN
CEDIPHVNEFSANDLFECNKLVFELSASDQPDRYKSHGKGYNWGNYNRKT
HKCEIFNVKPTCLINDKSYIATTALSHPIEVENNFP
Ligand information
>3sri Chain B (length=25) Species: 36329 (Plasmodium falciparum 3D7) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
KDIGAGPVASCFTTRMSPPQQICLN
Receptor-Ligand Complex Structure
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PDB3sri Structural and functional insights into the malaria parasite moving junction complex.
Resolution1.6 Å
Binding residue
(original residue number in PDB)
L131 Y142 R143 F183 P184 P185 T186 I190 G222 N223 N225 P226 S232 Y234 K235 Y236 Y251 A254 P350
Binding residue
(residue number reindexed from 1)
L24 Y35 R36 F76 P77 P78 T79 I83 G115 N116 N118 P119 S125 Y127 K128 Y129 Y144 A147 P231
Enzymatic activity
Enzyme Commision number ?
Gene Ontology

View graph for
Cellular Component
External links
PDB RCSB:3sri, PDBe:3sri, PDBj:3sri
PDBsum3sri
PubMed22737069
UniProtP50489|AMA1_PLAFC Apical membrane antigen 1 (Gene Name=AMA-1)

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