Structure of PDB 3shv Chain A Binding Site BS01
Receptor Information
>3shv Chain A (length=189) Species:
9606
(Homo sapiens) [
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KPTRTLVMTSMPSEKQNVVIQVVDKLKGFSIAPDVCETTTHVLSGKPLRT
LNVLLGIARGCWVLSYDWVLWSLELGHWISEEPFELSHHFPAAPLCRSEC
HLSAGPYRGTLFADQPAMFVSPASSPPVAKLCELVHLCGGRVSQVPRQAS
IVIGPYSGKKKATVKYLSEKWVLDSITQHKVCAPENYLL
Ligand information
>3shv Chain C (length=6) Species:
9606
(Homo sapiens) [
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QASQEY
Receptor-Ligand Complex Structure
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PDB
3shv
Specific recognition of phosphorylated tail of H2AX by the tandem BRCT domains of MCPH1 revealed by complex structure
Resolution
2.1 Å
Binding residue
(original residue number in PDB)
T653 S654 L692 R693 T694 P770
Binding residue
(residue number reindexed from 1)
T9 S10 L48 R49 T50 P126
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:3shv
,
PDBe:3shv
,
PDBj:3shv
PDBsum
3shv
PubMed
22154951
UniProt
Q8NEM0
|MCPH1_HUMAN Microcephalin (Gene Name=MCPH1)
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