Structure of PDB 3s8o Chain A Binding Site BS01

Receptor Information
>3s8o Chain A (length=101) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
EMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGN
DVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQ
V
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB3s8o Protein-ligand interactions: thermodynamic effects associated with increasing nonpolar surface area.
Resolution1.85 Å
Binding residue
(original residue number in PDB)
R67 R86 S88 S90 H107 F108 K109 L120 W121
Binding residue
(residue number reindexed from 1)
R14 R33 S35 S37 H54 F55 K56 L67 W68
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:3s8o, PDBe:3s8o, PDBj:3s8o
PDBsum3s8o
PubMed22007755
UniProtP62993|GRB2_HUMAN Growth factor receptor-bound protein 2 (Gene Name=GRB2)

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