Structure of PDB 3rzl Chain A Binding Site BS01

Receptor Information
>3rzl Chain A (length=194) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SHSWRHIRAEGLDSSYTVLFGKAEADEIFQELEKEVEYFTGALARVQVFG
KWHSVPRKQATYGDAGLTYTFSGLTLSPKPWIPVLERIRDHVSGVTGQTF
NFVLINRYKDGSDHICEHRDDERELAPGSPIASVSFGASRDFVFRHKAVV
RLPLAHGSLLMMNHPTNTHWYHSLPVRKKVLAPRVNLTFRKILL
Ligand information
Receptor-Ligand Complex Structure
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PDB3rzl Duplex interrogation by a direct DNA repair protein in search of base damage
Resolution2.6 Å
Binding residue
(original residue number in PDB)		V101 F102 H106 R110 F124 S125 H167 I168 C169 H171 E175 Y235
Binding residue
(residue number reindexed from 1)		V48 F49 H53 R57 F71 S72 H114 I115 C116 H118 E122 Y171
Enzymatic activity
Enzyme Commision number 1.14.11.33: DNA oxidative demethylase.
Gene Ontology

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Biological Process
External links
PDB RCSB:3rzl, PDBe:3rzl, PDBj:3rzl
PDBsum3rzl
PubMed22659876
UniProtQ6NS38|ALKB2_HUMAN DNA oxidative demethylase ALKBH2 (Gene Name=ALKBH2)

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