Structure of PDB 3rzj Chain A Binding Site BS01

Receptor Information
>3rzj Chain A (length=203) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GSHSWRHIRAEGLDSSYTVLFGKAEADEIFQELEKEVEYFTGALARVQVF
GKWHSVPRKQATYGDAGLTYTFSGLTLSPKPWIPVLERIRDHVSGVTGQT
FNFVLINRYKDGSDHICEHRDDERELAPGSPIASVSFGASRDFVFRHKDS
RPSRRVAVVRLPLAHGSLLMMNHPTNTHWYHSLPVRKKVLAPRVNLTFRK
ILL
Ligand information
Receptor-Ligand Complex Structure
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PDB3rzj Duplex interrogation by a direct DNA repair protein in search of base damage
Resolution2.5 Å
Binding residue
(original residue number in PDB)		V101 F102 H106 R110 F124 S125 H167 I168 C169 H171 R172 D173 E175 Y235
Binding residue
(residue number reindexed from 1)		V49 F50 H54 R58 F72 S73 H115 I116 C117 H119 R120 D121 E123 Y180
Enzymatic activity
Enzyme Commision number 1.14.11.33: DNA oxidative demethylase.
Gene Ontology

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Biological Process
External links
PDB RCSB:3rzj, PDBe:3rzj, PDBj:3rzj
PDBsum3rzj
PubMed22659876
UniProtQ6NS38|ALKB2_HUMAN DNA oxidative demethylase ALKBH2 (Gene Name=ALKBH2)

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