Structure of PDB 3rzh Chain A Binding Site BS01

Receptor Information
>3rzh Chain A (length=201) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
HSWRHIRAEGLDSSYTVLFGKAEADEIFQELEKEVEYFTGALARVQVFGK
WHSVPRKQATYGDAGLTYTFSGLTLSPKPWIPVLERIRDHVSGVTGQTFN
FVLINRYKDGSDHICEHRDDERELAPGSPIASVSFGASRDFVFRHKDSRP
SRRVAVVRLPLAHGSLLMMNHPTNTHWYHSLPVRKKVLAPRVNLTFRKIL
L
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB3rzh Duplex interrogation by a direct DNA repair protein in search of base damage
Resolution2.25 Å
Binding residue
(original residue number in PDB)		V101 F102 H106 R110 F124 S125 H167 I168 C169 H171 D173 E175 Y235
Binding residue
(residue number reindexed from 1)		V47 F48 H52 R56 F70 S71 H113 I114 C115 H117 D119 E121 Y178
Enzymatic activity
Enzyme Commision number 1.14.11.33: DNA oxidative demethylase.
Gene Ontology

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Biological Process
External links
PDB RCSB:3rzh, PDBe:3rzh, PDBj:3rzh
PDBsum3rzh
PubMed22659876
UniProtQ6NS38|ALKB2_HUMAN DNA oxidative demethylase ALKBH2 (Gene Name=ALKBH2)

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