Structure of PDB 3rtj Chain A Binding Site BS01

Receptor Information
>3rtj Chain A (length=258) Species: 3988 (Ricinus communis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
QYPIINFTTAGATVQSYTNFIRAVRGRLTTGADVRHEIPVLPNRVGLPIN
QRFILVELSNHAELSVTLALDVTNAYVVGYRAGNSAYFFHPDNQEDAEAI
THLFTDVQNRYTFAFGGNYDRLEQLAGNLRENIELGNGPLEEAISALYYY
STGGTQLPTLARSFIICIQMISEAARFQYIEGEMRTRIRYNRRSAPDPSV
ITLENSWGRLSTAIQESNQGAFASPIQLQRRNGSKFSVYDVSILIPIIAL
MVYRCAPP
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB3rtj X-ray analysis of substrate analogs in the ricin A-chain active site.
Resolution3.0 Å
Binding residue
(original residue number in PDB)
Y80 V81 G121 N122 Y123 D124 I172 E177 R180 E208 N209
Binding residue
(residue number reindexed from 1)
Y76 V77 G117 N118 Y119 D120 I168 E173 R176 E204 N205
Enzymatic activity
Catalytic site (original residue number in PDB) V81
Catalytic site (residue number reindexed from 1) V77
Enzyme Commision number 3.2.2.22: rRNA N-glycosylase.
Gene Ontology
Molecular Function
GO:0030598 rRNA N-glycosylase activity
Biological Process
GO:0017148 negative regulation of translation

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Molecular Function

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Biological Process
External links
PDB RCSB:3rtj, PDBe:3rtj, PDBj:3rtj
PDBsum3rtj
PubMed1433290
UniProtP02879|RICI_RICCO Ricin

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