Structure of PDB 3rsn Chain A Binding Site BS01

Receptor Information
>3rsn Chain A (length=165) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ENGRQLGEVELQCGICTKWFTADTFGIDTSSCLPFMTNYSFHCNVCHHSG
NTYFLRKQANLKEMCLSALANLTWQSRTQDEHPKTMFSKDKDIIPFIDKY
WECMTTRQRPGKMTWPNNIVKTMSKERDVFLVKEHPDPGSKDPEEDYPKF
GLLDQDLSNIGPAYD
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain3rsn Chain A Residue 200 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB3rsn Crystal structure of the N-terminal region of human Ash2L shows a winged-helix motif involved in DNA binding.
Resolution2.1 Å
Binding residue
(original residue number in PDB)		C23 C26 C56
Binding residue
(residue number reindexed from 1)		C13 C16 C46
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Cellular Component
GO:0048188 Set1C/COMPASS complex

View graph for
Cellular Component
External links
PDB RCSB:3rsn, PDBe:3rsn, PDBj:3rsn
PDBsum3rsn
PubMed21660059
UniProtQ9UBL3|ASH2L_HUMAN Set1/Ash2 histone methyltransferase complex subunit ASH2 (Gene Name=ASH2L)

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