Structure of PDB 3ro2 Chain A Binding Site BS01
Receptor Information
>3ro2 Chain A (length=328) Species:
10090
(Mus musculus) [
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GSASCLELALEGERLCKSGDCRAGVSFFEAAVQVGTEDLKTLSAIYSQLG
NAYFYLHDYAKALEYHHHDLTLARTIGDQLGEAKASGNLGNTLKVLGNFD
EAIVCCQRHLDISRELNDKVGEARALYNLGNVYHAKGKSFGCPGPQFPED
VRNALQAAVDLYEENLSLVTALGDRAAQGRAFGNLGNTHYLLGNFRDAVI
AHEQRLLIAKEFGDKAAERRAYSNLGNAYIFLGEFETASEYYKKTLLLAR
QLKDRAVEAQSCYSLGNTYTLLQDYEKAIDYHLKHLAIAQELKDRIGEGR
ACWSLGNAYTALGNHDQAMHFAEKHLEI
Ligand information
>3ro2 Chain B (length=22) Species:
9606
(Homo sapiens) [
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FYMGTCQDEPEQLDDWNRIAEL
Receptor-Ligand Complex Structure
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PDB
3ro2
LGN/mInsc and LGN/NuMA complex structures suggest distinct functions in asymmetric cell division for the Par3/mInsc/LGN and G[alpha]i/LGN/NuMA pathways
Resolution
2.3 Å
Binding residue
(original residue number in PDB)
L22 E25 C28 K29 K52 S59 Q60 N63 A64 F66 K96 K150 R196 N203 R221 R235 R236 N240 N243 I246 Q276 Y279 S280 N283 R316
Binding residue
(residue number reindexed from 1)
L10 E13 C16 K17 K40 S47 Q48 N51 A52 F54 K84 K138 R180 N187 R205 R219 R220 N224 N227 I230 Q260 Y263 S264 N267 R300
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:3ro2
,
PDBe:3ro2
,
PDBj:3ro2
PDBsum
3ro2
PubMed
21816348
UniProt
Q8VDU0
|GPSM2_MOUSE G-protein-signaling modulator 2 (Gene Name=Gpsm2)
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