Structure of PDB 3rl2 Chain A Binding Site BS01

Receptor Information
>3rl2 Chain A (length=274) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GSHSMRYFFTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDAASQRMEPRAP
WIEQEGPEYWDQETRNVKAQSQTDRVDLGTLRGYYNQSEAGSHTIQIMYG
CDVGSDGRFLRGYRQDAYDGKDYIALNEDLRSWTAADMAAQITKRKWEAA
HEAEQLRAYLDGTCVEWLRRYLENGKETLQRTDPPKTHMTHHPISDHEAT
LRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVP
SGEEQRYTCHVQHEGLPKPLTLRW
Ligand information
>3rl2 Chain C (length=10) Species: 11676 (Human immunodeficiency virus 1) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
QVPLRPMTYK
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB3rl2 Structural basis of cross-allele presentation by HLA-A*0301 and HLA-A*1101 revealed by two HIV-derived peptide complexes
Resolution2.386 Å
Binding residue
(original residue number in PDB)
Y7 E63 N66 T73 V76 D77 Y84 Y99 R114 D116 T143 K146 W147 E152 Q155 Y159 W167 Y171
Binding residue
(residue number reindexed from 1)
Y7 E63 N66 T73 V76 D77 Y84 Y99 R114 D116 T143 K146 W147 E152 Q155 Y159 W167 Y171
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:3rl2, PDBe:3rl2, PDBj:3rl2
PDBsum3rl2
PubMed21943705
UniProtP04439|HLAA_HUMAN HLA class I histocompatibility antigen, A alpha chain (Gene Name=HLA-A)

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