Structure of PDB 3ri4 Chain A Binding Site BS01

Receptor Information
>3ri4 Chain A (length=136) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GTFKDYVRDRADLNKDKPVIPAAALAGYTGSGPIQLWQFLLELLTDKSCQ
SFISWTGDGWEFKLSDPDEVARRWGKRKNKPKMNYEKLSRGLRYYYDKNI
IHKTAGKRYVYRFVCDLQSLLGYTPEELHAMLDVKP
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB3ri4 Structural basis of ets1 cooperative binding to widely separated sites on promoter DNA.
Resolution3.0 Å
Binding residue
(original residue number in PDB)		Q336 L337 W375 K379 M384 K388 R391 Y395 Y396 K399
Binding residue
(residue number reindexed from 1)		Q35 L36 W74 K78 M83 K87 R90 Y94 Y95 K98
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003700 DNA-binding transcription factor activity
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0006355 regulation of DNA-templated transcription
GO:0006357 regulation of transcription by RNA polymerase II

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Molecular Function
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Biological Process
External links
PDB RCSB:3ri4, PDBe:3ri4, PDBj:3ri4
PDBsum3ri4
PubMed22432043
UniProtP14921|ETS1_HUMAN Protein C-ets-1 (Gene Name=ETS1)

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