Structure of PDB 3rew Chain A Binding Site BS01

Receptor Information
>3rew Chain A (length=271) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GSHSMRYFFTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDAASQRMEPRAP
WIEQEGPEYWDGETRKVKAHSQTHRVDLGTLRGYYNQSEAGSHTVQRMYG
CDVGSDWRFLRGYHQYAYDGKDYIALKEDLRSWTAADMAAQTTKHKWEAA
HVAEQLRAYLEGTCVEWLRRYLENGKETLQRTDAPKTHMTHHAEATLRCW
ALSFYPAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVPSGQE
QRYTCHVQHEGLPKPLTLRWE
Ligand information
>3rew Chain C (length=9) Species: 10377 (Human herpesvirus 4 strain B95-8) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
CLGGLLTMV
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB3rew Structural and energetic evidence for highly peptide-specific tumor antigen targeting via allo-MHC restriction.
Resolution1.9 Å
Binding residue
(original residue number in PDB)		Y7 F9 M45 E63 V67 H70 T73 D77 Y84 R97 Y99 Y116 T143 K146 W147 Q155 Y159 W167 Y171
Binding residue
(residue number reindexed from 1)		Y7 F9 M45 E63 V67 H70 T73 D77 Y84 R97 Y99 Y116 T143 K146 W147 Q155 Y159 W167 Y171
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:3rew, PDBe:3rew, PDBj:3rew
PDBsum3rew
PubMed22160697
UniProtP04439|HLAA_HUMAN HLA class I histocompatibility antigen, A alpha chain (Gene Name=HLA-A)

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