Structure of PDB 3rbx Chain A Binding Site BS01

Receptor Information
>3rbx Chain A (length=221) Species: 187420 (Methanothermobacter thermautotrophicus str. Delta H) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
RHVVICGWSESTLECLRELRGSEVFVLAEDENVRKKVLRSGANFVHGDPT
RVSDLEKANVRGARAVIVNLESDSETIHCILGIRKIDESVRIIAEAERYE
NIEQLRMAGADQVISPFVISGRLMSRSIDDGYEAMFVQDVLAEESTRRMV
EVPIPEGSKLEGVSVLDADIHDVTGVIIIGVGRGDELIIDPPRDYSFRAG
DIILGIGKPEEIERLKNYISA
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain3rbx Chain A Residue 600 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB3rbx Structures of multiple Ca2+-binding sites in a K+ channel RCK domain
Resolution2.8 Å
Binding residue
(original residue number in PDB)		R241 D245 E248
Binding residue
(residue number reindexed from 1)		R126 D130 E133
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0008324 monoatomic cation transmembrane transporter activity
Biological Process
GO:0006813 potassium ion transport

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:3rbx, PDBe:3rbx, PDBj:3rbx
PDBsum3rbx
PubMed
UniProtO27564|MTHK_METTH Calcium-gated potassium channel MthK (Gene Name=mthK)

[Back to BioLiP]