Structure of PDB 3rab Chain A Binding Site BS01

Receptor Information
>3rab Chain A (length=169) Species: 10116 (Rattus norvegicus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
NFDYMFKILIIGNSSVGKTSFLFRYADDSFTPAFVSTVGIDFKVKTIYRN
DKRIKLQIWDTAGQERYRTITTAYYRGAMGFILMYDITNEESFNAVQDWS
TQIKTYSWDNAQVLLVGNKCDMEDERVVSSERGRQLADHLGFEFFEASAK
DNINVKQTFERLVDVICEK
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain3rab Chain A Residue 201 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB3rab Structural basis of activation and GTP hydrolysis in Rab proteins.
Resolution2.0 Å
Binding residue
(original residue number in PDB)		T36 T54
Binding residue
(residue number reindexed from 1)		T19 T37
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003924 GTPase activity
GO:0005525 GTP binding

View graph for
Molecular Function
External links
PDB RCSB:3rab, PDBe:3rab, PDBj:3rab
PDBsum3rab
PubMed10196122
UniProtP63012|RAB3A_RAT Ras-related protein Rab-3A (Gene Name=Rab3a)

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