Structure of PDB 3r0x Chain A Binding Site BS01

Receptor Information
>3r0x Chain A (length=438) Species: 90371 (Salmonella enterica subsp. enterica serovar Typhimurium) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MENIQKLIARYPLVEDLVALKETTWFNPGATSLAQGLPYVGLTEQDVNAA
HDRLARFAPYLAKAFPQTAAAGGMIESDVVAIPAMQKRLEKEYGQTINGE
MLLKKDSHLAISGSIKARGGIYEVLTHAEKLALEAGLLTTDDDYSVLLSP
EFKQFFSQYSIAVGSTGNLGLSIGIMSACIGFKVTVHMSADARAWKKAKL
RSHGVTVVEYEDDYGVAVEQGRKAAQSDPNCFFIDDENSRTLFLGYAVAG
QRLKAQFAQQGRVVDASHPLFVYLPCGVGGGPGGVAFGLKLAFGDNVHCF
FAEPTHSPCMLLGVYTGLHDAISVQDIGIDNLTAADGLAVGRASGFVGRA
MERLLDGLYTLDDQTMYDMLGWLAQEEGIRLEPSALAGMAGPQRICASVA
YQQRHGFSQTQLGNATHLVWATGGGMVPEDEMEQYLAK
Ligand information
Ligand IDNA
InChIInChI=1S/Na/q+1
InChIKeyFKNQFGJONOIPTF-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
CACTVS 3.341
OpenEye OEToolkits 1.5.0		[Na+]
FormulaNa
NameSODIUM ION
ChEMBL
DrugBankDB14516
ZINC
PDB chain3r0x Chain A Residue 454 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB3r0x Crystal structures of open and closed forms of D-serine deaminase from Salmonella typhimurium - implications on substrate specificity and catalysis
Resolution1.93 Å
Binding residue
(original residue number in PDB)		C276 G277 E303 S307 C309 L338 V340
Binding residue
(residue number reindexed from 1)		C276 G277 E303 S307 C309 L338 V340
Annotation score1
Enzymatic activity
Enzyme Commision number 4.3.1.18: D-serine ammonia-lyase.
Gene Ontology
Molecular Function
GO:0008721 D-serine ammonia-lyase activity
GO:0016829 lyase activity
GO:0016836 hydro-lyase activity
GO:0030170 pyridoxal phosphate binding
Biological Process
GO:0006520 amino acid metabolic process
GO:0009097 isoleucine biosynthetic process
GO:0036088 D-serine catabolic process
GO:0046416 D-amino acid metabolic process

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Molecular Function
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Biological Process
External links
PDB RCSB:3r0x, PDBe:3r0x, PDBj:3r0x
PDBsum3r0x
PubMed21668644
UniProtQ8ZL08|SDHD_SALTY D-serine dehydratase (Gene Name=dsdA)

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