Structure of PDB 3qm2 Chain A Binding Site BS01

Receptor Information
>3qm2 Chain A (length=330) Species: 90371 (Salmonella enterica subsp. enterica serovar Typhimurium) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
QVFNFSSGPAMLPAEVLKLAQQEVAEEAEQDFRDLLNIPSNYKVLFCHGG
GRGQFAGVPLNLLGDKTTADYVDAGYWAASAIKEAKKYCAPQIIDAKITV
DGKRAVKPMREWQLSDNAAYLHYCPNETIDGIAIDETPDFGPEVVVTADF
SSTILSAPLDVSRYGVIYAGAQKNIGPAGLTLVIVREDLLGKAHESCPSI
LDYTVLNDNPTFAWYLSGLVFKWLKAQGGVAAMHKINQQKAELLYGVIDN
SDFYRNDVAQANRSRMNVPFQLADNTLDKVFLEESFAAGLHALKGHRVVG
GMRASIYNAMPIEGVKALTDFMIDFERRHG
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain3qm2 Chain A Residue 363 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB3qm2 2.25 Angstrom Crystal Structure of Phosphoserine Aminotransferase (SerC) from Salmonella enterica subsp. enterica serovar Typhimurium.
Resolution2.25 Å
Binding residue
(original residue number in PDB)		I280 D281 S283 Y286
Binding residue
(residue number reindexed from 1)		I248 D249 S251 Y254
Annotation score1
Enzymatic activity
Catalytic site (original residue number in PDB) W102 D174 K198
Catalytic site (residue number reindexed from 1) W77 D149 K173
Enzyme Commision number 2.6.1.52: phosphoserine transaminase.
Gene Ontology
Molecular Function
GO:0004648 O-phospho-L-serine:2-oxoglutarate aminotransferase activity
GO:0008483 transaminase activity
GO:0030170 pyridoxal phosphate binding
Biological Process
GO:0006563 L-serine metabolic process
GO:0006564 L-serine biosynthetic process
GO:0008615 pyridoxine biosynthetic process
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:3qm2, PDBe:3qm2, PDBj:3qm2
PDBsum3qm2
PubMed
UniProtP55900|SERC_SALTY Phosphoserine aminotransferase (Gene Name=serC)

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