Structure of PDB 3qeq Chain A Binding Site BS01
Receptor Information
>3qeq Chain A (length=275) Species:
9606
(Homo sapiens) [
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GSHSMRYFFTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDAASQRMEPRAP
WIEQEGPEYWDGETRKVKAHSQTHRVDLGTLRGYYNQSEAGSHTVQRMYG
CDVGSDWRFLRGYHQYAYDGKDYIALKEDLRSWTAADMAAQTTKHKWEAA
HVAEQLRAYLEGTCVEWLRRYLENGKETLQRTDAPKTHMTHHAVSDHEAT
LRCWALSFYPAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVP
SGQEQRYTCHVQHEGLPKPLTLRWE
Ligand information
>3qeq Chain C (length=9) Species:
9606
(Homo sapiens) [
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AAGIGILTV
Receptor-Ligand Complex Structure
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PDB
3qeq
TCRs Used in Cancer Gene Therapy Cross-React with MART-1/Melan-A Tumor Antigens via Distinct Mechanisms.
Resolution
2.59 Å
Binding residue
(original residue number in PDB)
Y7 E63 K66 T73 V76 D77 R97 Y99 T143 K146 W147 Y159 W167 Y171
Binding residue
(residue number reindexed from 1)
Y7 E63 K66 T73 V76 D77 R97 Y99 T143 K146 W147 Y159 W167 Y171
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:3qeq
,
PDBe:3qeq
,
PDBj:3qeq
PDBsum
3qeq
PubMed
21795600
UniProt
P04439
|HLAA_HUMAN HLA class I histocompatibility antigen, A alpha chain (Gene Name=HLA-A)
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