Structure of PDB 3q1i Chain A Binding Site BS01
Receptor Information
>3q1i Chain A (length=216) Species:
9606
(Homo sapiens) [
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CHLSDMLQQLHSVNASKPSERGLVRQEEAEDPACIPIFWVSKWVDYSDKY
GLGYQLCDNSVGVLFNDSTRLILYNDGDSLQYIERDGTESYLTVSSHPNS
LMKKITLLKYFRNYMSEHLLKAGANITPRLPYLRTWFRTRSAIILHLSNG
SVQINFFQDHTKLILCPLMAAVTYIDEKRDFRTYRLSLLEEYGCCKELAS
RLRYARTMVDKLLSSR
Ligand information
>3q1i Chain E (length=7) Species:
9606
(Homo sapiens) [
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PPPMSSM
Receptor-Ligand Complex Structure
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PDB
3q1i
From crystal packing to molecular recognition: prediction and discovery of a binding site on the surface of polo-like kinase 1
Resolution
1.4 Å
Binding residue
(original residue number in PDB)
W414 D416 Y485 H489 L490 L491 R516 H538 K540
Binding residue
(residue number reindexed from 1)
W43 D45 Y114 H118 L119 L120 R138 H160 K162
Enzymatic activity
Enzyme Commision number
2.7.11.21
: polo kinase.
External links
PDB
RCSB:3q1i
,
PDBe:3q1i
,
PDBj:3q1i
PDBsum
3q1i
PubMed
21472932
UniProt
P53350
|PLK1_HUMAN Serine/threonine-protein kinase PLK1 (Gene Name=PLK1)
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