Structure of PDB 3q0m Chain A Binding Site BS01

Receptor Information
>3q0m Chain A (length=337) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
RSRLLEDFRNNRYPNLQLREIAGHIMEFSQDQHGSRFIQLKLERATPAER
QLVFNEILQAAYQLMVDVFGNYVIQKFFEFGSLEQKLALAERIRGHVLSL
ALQMYGCRVIQKALEFIPSDQQNEMVRELDGHVLKCVKDQNGNHVVQKCI
ECVQPQSLQFIIDAFKGQVFALSTHPYGCRVIQRILEHCLPDQTLPILEE
LHQHTEQLVQDQYGNYVIQHVLEHGRPEDKSKIVAEIRGNVLVLSQHKFA
SNVVEKCVTHASRTERAVLIDEVCTMNDGPHSALYTMMKDQYANYVVQKM
IDVAEPGQRKIVMHKIRPHIATLRKYTYGKHILAKLE
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB3q0m Alternate modes of cognate RNA recognition by human PUMILIO proteins.
Resolution2.705 Å
Binding residue
(original residue number in PDB)		Q860 R864 Q867 N899 Y900 R936 Q939 Q968 H972 Q975 Y1005 R1008 Q1011 N1043 Y1044 Q1047 S1079 N1080 E1083 N1122 Y1123 Q1126 Y1156 H1159
Binding residue
(residue number reindexed from 1)		Q32 R36 Q39 N71 Y72 R108 Q111 Q140 H144 Q147 Y177 R180 Q183 N215 Y216 Q219 S251 N252 E255 N294 Y295 Q298 Y328 H331
Binding affinityPDBbind-CN: Kd=0.63nM
Enzymatic activity
Enzyme Commision number ?
Gene Ontology

View graph for
Molecular Function
External links
PDB RCSB:3q0m, PDBe:3q0m, PDBj:3q0m
PDBsum3q0m
PubMed21397187
UniProtQ14671|PUM1_HUMAN Pumilio homolog 1 (Gene Name=PUM1)

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