Structure of PDB 3q0d Chain A Binding Site BS01
Receptor Information
>3q0d Chain A (length=145) Species:
3702
(Arabidopsis thaliana) [
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QIIGTVPGVEVGDEFQYRMELNLLGIHRPSQSGIDYMKDGELVATSIVSS
GGYNDVLDNSDVLIYTGQGGNVEPPKDQQLVTGNLALKNSINKKNPVRVI
RGIKKNYVYDGLYLVEEYWEETGSHGKLVFKFKLRRIPGQPELPW
Ligand information
>3q0d Chain B (length=10) [
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tccacgtcag
Receptor-Ligand Complex Structure
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PDB
3q0d
A dual flip-out mechanism for 5mC recognition by the Arabidopsis SUVH5 SRA domain and its impact on DNA methylation and H3K9 dimethylation in vivo.
Resolution
2.3704 Å
Binding residue
(original residue number in PDB)
Y378 R379 S391 Q392 S393 G394 S412 S413 G415 Y416 D418 Y428 T429 Q431
Binding residue
(residue number reindexed from 1)
Y17 R18 S30 Q31 S32 G33 S49 S50 G52 Y53 D55 Y65 T66 Q68
Binding affinity
PDBbind-CN
: Kd=5uM
Enzymatic activity
Enzyme Commision number
2.1.1.-
2.1.1.367
: [histone H3]-lysine(9) N-methyltransferase.
External links
PDB
RCSB:3q0d
,
PDBe:3q0d
,
PDBj:3q0d
PDBsum
3q0d
PubMed
21245167
UniProt
O82175
|SUVH5_ARATH Histone-lysine N-methyltransferase, H3 lysine-9 specific SUVH5 (Gene Name=SUVH5)
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