Structure of PDB 3pkm Chain A Binding Site BS01

Receptor Information
>3pkm Chain A (length=229) Species: 2261 (Pyrococcus furiosus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
HHHHGSRFLIRLVAFKVPYNHQYYLQGLIYNAIKSSNPKLATYLHEVKGP
KLFTYSLFMAEKREHPYFLGYKKGFFYFSTCVPEIAEALVNGLLMNPEVR
LWDERFYLHEIKVLREPKKFNGSTFVTLSPIAVTVVYDVPPMEKEFYSII
KDDLQDKYVMAYGDKPPSEFEMEVLIAKPKRFRIKPGIYQTAWHLVFRAY
GNDDLLKVGYEVGFGEKNSLGFGMVKVEG
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB3pkm Interaction of the Cas6 Riboendonuclease with CRISPR RNAs: Recognition and Cleavage.
Resolution3.103 Å
Binding residue
(original residue number in PDB)		L10 R12 Y26 N27 M66 R70 H72 F86 Y153 K194 P195 K196 R197 Y205 T207 H210 E244
Binding residue
(residue number reindexed from 1)		L9 R11 Y19 N20 M59 R63 H65 F75 Y137 K178 P179 K180 R181 Y189 T191 H194 E228
Enzymatic activity
Enzyme Commision number 3.1.-.-
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0004519 endonuclease activity
GO:0016788 hydrolase activity, acting on ester bonds
Biological Process
GO:0043571 maintenance of CRISPR repeat elements
GO:0051607 defense response to virus

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Molecular Function
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Biological Process
External links
PDB RCSB:3pkm, PDBe:3pkm, PDBj:3pkm
PDBsum3pkm
PubMed21300293
UniProtQ8U1S4|CAS6_PYRFU CRISPR-associated endoribonuclease Cas6 (Gene Name=cas6)

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