Structure of PDB 3pjz Chain A Binding Site BS01

Receptor Information
>3pjz Chain A (length=468) Species: 670 (Vibrio parahaemolyticus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MQFRSIIRIVGLLLALFSVTMLAPALVALLYRDGAGVPFVTTFFVLLFCG
AMCWFPNRRHKHELKSRDGFLIVVLFWTVLGSAGSLPFLIADNPNISVTD
AFFESFSALTTTGATVIVGLDELPKAILFYRQFLQWFGGMGIIVLAVAIL
PVLGIGGMTPRIAETAKALWYIYLSLTIACAVAFWLAGMTPFDAISHSFS
TIAIGGFSTHDASMGYFDSYAINLITVVFLLISACNFTLHFAAFASGGVH
PKYYWKDPEFRAFIFIQVLLFLVCFLLLLKHHSYTSPYDAFDQALFQTVS
ISTTAGFTTTGFADWPLFLPVLLLFSSFIGGCAGSTGGGMKVIRILLLTL
QGARELKRLVHPRAVYTIKVGGSALPQRVVDAVWGFFSAYALVFVVCMLG
LIATGMDELSAFSAVAATLNNLGPGLGEVALHFGDVNDKAKWVLIVSMLF
GRLEIFTLLILLTPTFWR
Ligand information
Ligand IDK
InChIInChI=1S/K/q+1
InChIKeyNPYPAHLBTDXSSS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
CACTVS 3.341
OpenEye OEToolkits 1.5.0		[K+]
FormulaK
NamePOTASSIUM ION
ChEMBLCHEMBL1233793
DrugBankDB01345
ZINC
PDB chain3pjz Chain A Residue 501 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB3pjz Crystal structure of a potassium ion transporter, TrkH.
Resolution3.506 Å
Binding residue
(original residue number in PDB)		T111 T112 G113 I220 G221 G222 T320 A321 G322 N437 L438
Binding residue
(residue number reindexed from 1)		T111 T112 G113 I204 G205 G206 T304 A305 G306 N421 L422
Annotation score5
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005267 potassium channel activity
GO:0008324 monoatomic cation transmembrane transporter activity
GO:0015379 potassium:chloride symporter activity
GO:0030955 potassium ion binding
GO:0042802 identical protein binding
GO:0042803 protein homodimerization activity
GO:0046872 metal ion binding
Biological Process
GO:0006812 monoatomic cation transport
GO:0006813 potassium ion transport
GO:0030001 metal ion transport
GO:0034220 monoatomic ion transmembrane transport
GO:0055085 transmembrane transport
GO:0071805 potassium ion transmembrane transport
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:3pjz, PDBe:3pjz, PDBj:3pjz
PDBsum3pjz
PubMed21317882
UniProtQ87TN7|TRKH_VIBPA Trk system potassium uptake protein TrkH (Gene Name=trkH)

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