Structure of PDB 3pih Chain A Binding Site BS01

Receptor Information
>3pih Chain A (length=836) Species: 2336 (Thermotoga maritima) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
NEIVVKGARVHNLKNITVRIPKNRLVVITGVSGSGKSSLAMDTIYAEGQR
RYLESLSTYKKPDVDEIEGLSPAIAIDQKTSHNPRSTVGTVTEIYDYLRV
LYARIGKAHCPECGRPLEKKSIDEILQDLFNSFKEGSRIYILAPLVVDRL
ILETRNEHRILDSLELAMREGKGFVEIRNVDTGESKIFSENLMCPVCGIG
FPEITPKLFSFNSPYGACPNCHGLGFTFEVDPSLVAIIPYRWDRRLSRWV
AREIEKRGVSPPEDVKEFILYGDFEGVVPKVQRWHRETEMKEWLEKNFIV
QRTCSVCGGRRLNREALSVKINGLNIHEFTELSISEELEFLKNLNLTERE
REIVGELLKEIEKRLEFLVDVGLEYLTLSRSATTLSGGESQRIRLATQIG
SGLTGVIYVLDEPTIGLHPRDTERLIKTLKKLRDLGNTVIVVEHDEEVIR
NADHIIDIGPGGGTNGGRVVFQGTVDELLKNPDSSLTGEYLSGKRKITVN
KTRRLPYASLKIKGVRHNNLKNIDVEIPLGVFVCVTGVSGSGKSSLVMET
LYPALMNLLHKTKLPAGEFDSIEGHENIDKMIAIDQSPIGRTPRSNPATY
TKVFDEIRSLFAMTPAAKARGYNKSRFSFNLKGGRCEACQGQGYVKIEML
FLPDVYVECDVCKGKRYNRETLEITYKGKNISDILDMTVDEALEFFKNIP
SIKRTLQVLHDVGLGYVKLGQPATTLSGGEAQRIKLASELRKRDTGRTLY
ILDEPTVGLHFEDVRKLVEVLHRLVDRGNTVIVIEHNLDVIKNADHIIDL
GPEGGKEGGYIVATGTPEEIAKNPHSYTGRFLKNVL
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB3pih Structure of UvrA nucleotide excision repair protein in complex with modified DNA.
Resolution2.9 Å
Binding residue
(original residue number in PDB)		G670 S675 T679 Y680 R688 S705 S708 N710 L711
Binding residue
(residue number reindexed from 1)		G590 S595 T599 Y600 R608 S625 S628 N630 L631
Binding affinityPDBbind-CN: Kd=1.9nM
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003824 catalytic activity
GO:0004518 nuclease activity
GO:0005524 ATP binding
GO:0008270 zinc ion binding
GO:0009381 excinuclease ABC activity
GO:0016887 ATP hydrolysis activity
GO:0046872 metal ion binding
Biological Process
GO:0006281 DNA repair
GO:0006289 nucleotide-excision repair
GO:0009432 SOS response
Cellular Component
GO:0005737 cytoplasm
GO:0009380 excinuclease repair complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:3pih, PDBe:3pih, PDBj:3pih
PDBsum3pih
PubMed21240268
UniProtQ9WYV0|UVRA_THEMA UvrABC system protein A (Gene Name=uvrA)

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