Structure of PDB 3pgc Chain A Binding Site BS01

Receptor Information
>3pgc Chain A (length=177) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
EHVIIQAEFYLNPDQSGEFMFDFDGDEIFHVDMAKKETVWRLEEFGRFAS
FEAQGALANIAVDKANLEIMTKRSNYTPITNVPPEVTVLTNSPVELREPN
VLICFIDKFTPPVVNVTWLRNGKPVTTGVSETVFLPREDHLFRKFHYLPF
LPSTEDVYDCRVEHWGLDEPLLKHWEF
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB3pgc Bidirectional binding of invariant chain peptides to an MHC class II molecule.
Resolution2.66 Å
Binding residue
(original residue number in PDB)		Q9 R50 F51 A52 S53 F54 G58 N62 N69 I72
Binding residue
(residue number reindexed from 1)		Q6 R47 F48 A49 S50 F51 G55 N59 N66 I69
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0006955 immune response
GO:0019882 antigen processing and presentation
Cellular Component
GO:0016020 membrane
GO:0042613 MHC class II protein complex

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Biological Process
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Cellular Component
External links
PDB RCSB:3pgc, PDBe:3pgc, PDBj:3pgc
PDBsum3pgc
PubMed21115828
UniProtP01903|DRA_HUMAN HLA class II histocompatibility antigen, DR alpha chain (Gene Name=HLA-DRA)

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