Structure of PDB 3pew Chain A Binding Site BS01

Receptor Information
>3pew Chain A (length=391) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
AKSFDELGLAPELLKGIYAMKFQKPSKIQERALPLLLHNPPRNMIAQSQS
GTGKTAAFSLTMLTRVNPEDASPQAICLAPSRELARQTLEVVQEMGKFTK
ITSQLIVPDSFEKNKQINAQVIVGTPGTVLDLMRRKLMQLQKIKIFVLDE
ADNMLDQQGLGDQCIRVKRFLPKDTQLVLFSATFADAVRQYAKKIVPNAN
TLELQTNEVNVDAIKQLYMDCKNEADKFDVLTELYGVMTIGSSIIFVATK
KTANVLYGKLKSEGHEVSILHGDLQTQERDRLIDDFREGRSKVLITTNVL
ARGIDIPTVSMVVNYDLPTLANGQADPATYIHRIGRTGRFGRKGVAISFV
HDKNSFNILSAIQKYFGDIEMTRVPTDDWDEVEKIVKKVLK
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB3pew A conserved mechanism of DEAD-box ATPase activation by nucleoporins and InsP(6) in mRNA export.
Resolution1.501 Å
Binding residue
(original residue number in PDB)		P170 S171 P198 T215 G217 T218 Q247 Q248 G249 L250 Q253 A338 T339 K340 H361 G362 R369 T387 V389
Binding residue
(residue number reindexed from 1)		P80 S81 P108 T125 G127 T128 Q157 Q158 G159 L160 Q163 A248 T249 K250 H271 G272 R279 T297 V299
Enzymatic activity
Enzyme Commision number 3.6.4.13: RNA helicase.
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003724 RNA helicase activity
GO:0005524 ATP binding

View graph for
Molecular Function
External links
PDB RCSB:3pew, PDBe:3pew, PDBj:3pew
PDBsum3pew
PubMed21441902
UniProtP20449|DBP5_YEAST ATP-dependent RNA helicase DBP5 (Gene Name=DBP5)

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