Structure of PDB 3pdo Chain A Binding Site BS01

Receptor Information
>3pdo Chain A (length=185) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MIKEEHVIIQAEFYLNPDQSGEFMFDFDGDEIFHVDMAKKETVWRLEEFG
RFASFEAQGALANIAVDKANLEIMTKRSNYTPITNVPPEVTVLTNSPVEL
REPNVLICFIDKFTPPVVNVTWLRNGKPVTTGVSETVFLPREDHLFRKFH
YLPFLPSTEDVYDCRVEHWGLDEPLLKHWEFDAPS
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB3pdo Bidirectional binding of invariant chain peptides to an MHC class II molecule.
Resolution1.95 Å
Binding residue
(original residue number in PDB)
Q9 R50 F51 A52 S53 F54 G58 N62 N69 M73
Binding residue
(residue number reindexed from 1)
Q10 R51 F52 A53 S54 F55 G59 N63 N70 M74
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0006955 immune response
GO:0019882 antigen processing and presentation
Cellular Component
GO:0016020 membrane
GO:0042613 MHC class II protein complex

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Biological Process

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Cellular Component
External links
PDB RCSB:3pdo, PDBe:3pdo, PDBj:3pdo
PDBsum3pdo
PubMed21115828
UniProtP01903|DRA_HUMAN HLA class II histocompatibility antigen, DR alpha chain (Gene Name=HLA-DRA)

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