Structure of PDB 3pcs Chain A Binding Site BS01

Receptor Information

>3pcs Chain A (length=350) Species: 83334 (Escherichia coli O157:H7) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

KKSWDEMSCAEKLFKVLSFGLWNPTYSRSERQSFQELLTVLEPVYPLPNE
LGRVSARFSDGSSLRISVTNSELVEAEIRTANNEKITVLLESNEQNRLLQ
SLPIDRHMPYIQVHRALLTDTTSMRNLLGFTSKLSTTLIPHNAQTDPLSG
PTPFSSIFMDTCRGLGNAKLSLNGVDIPANAQKLLRDALGLKDTHSSPTR
NVIDHGISRHDAEQIARESSGSDKQKAEVVEFLCHPEAATAICSAFYQSF
NVPALTLTHERISKASEYNAERSTPNACINISISQSSDGNIYVTSHTGVL
IMAPEDRPNEMGMLTNRTSYEVPQGVKCIIDEMVSALQPRYAASETYLQN

Ligand information

>3pcs Chain E (length=14) Species: 9606 (Homo sapiens) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

AVLDVLKFYDSNTV

Receptor-Ligand Complex Structure

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Structure summary

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PDB	3pcs The assembly of a GTPase-kinase signalling complex by a bacterial catalytic scaffold.
Resolution	2.86 Å
Binding residue (original residue number in PDB)	T166 G211 N212 Q293 S294 P322 N323 A324 T344
Binding residue (residue number reindexed from 1)	T121 G166 N167 Q248 S249 P275 N276 A277 T297

Enzymatic activity

Enzyme Commision number

Gene Ontology

	Molecular Function
GO:0004197	cysteine-type endopeptidase activity

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Molecular Function

External links

PDB	RCSB:3pcs, PDBe:3pcs, PDBj:3pcs
PDBsum	3pcs
PubMed	21170023
UniProt	Q7DB50

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