Structure of PDB 3p72 Chain A Binding Site BS01
Receptor Information
>3p72 Chain A (length=269) Species:
9606
(Homo sapiens) [
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HPICEVSKVASHLEVNCDKRQLTALPPDLPKDTTILHLSENLLYTFSLAT
LMPYTRLTQLNLDRCELTKLQVDGTLPVLGTLDLSHNQLQSLPLLGQTLP
ALTVLDVSFNRLTSLPLGALRGLGELQELYLKGNELKTLPPGLLTPTPKL
EKLSLANNQLTELPAGLLNGLENLDTLLLQENSLYTIPKGFFGSHLLPFA
FLHGNPWLCNCEILYFRRWLQDNAENVYVWKQGVDVKAMTSNVASVQCDN
SDKFPVYKYPGKGCPLVPR
Ligand information
>3p72 Chain B (length=11) [
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CTERMALHNLC
Receptor-Ligand Complex Structure
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PDB
3p72
Glycoprotein Ibalpha inhibitor complex structure reveals a combined steric and allosteric mechanism of von Willebrand factor antagonism.
Resolution
1.9 Å
Binding residue
(original residue number in PDB)
E128 Y130 K132 S154 W230 D235 V236 K237
Binding residue
(residue number reindexed from 1)
E128 Y130 K132 S154 W230 D235 V236 K237
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:3p72
,
PDBe:3p72
,
PDBj:3p72
PDBsum
3p72
PubMed
19726719
UniProt
P07359
|GP1BA_HUMAN Platelet glycoprotein Ib alpha chain (Gene Name=GP1BA)
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