Structure of PDB 3p34 Chain A Binding Site BS01
Receptor Information
>3p34 Chain A (length=230) Species:
9606
(Homo sapiens) [
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GPLGSPEFDCHLSDMLQQLHSVNASKPSERGLVRQEEAEDPACIPIFWVS
KWVDYSDKYGLGYQLCDNSVGVLFNDSTRLILYNDGDSLQYIERDGTESY
LTVSSHPNSLMKKITLLKYFRNYMSEHLLKAGANITPREGDELARLPYLR
TWFRTRSAIILHLSNGSVQINFFQDHTKLILCPLMAAVTYIDEKRDFRTY
RLSLLEEYGCCKELASRLRYARTMVDKLLS
Ligand information
>3p34 Chain B (length=6) [
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MQSTPL
Receptor-Ligand Complex Structure
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PDB
3p34
From crystal packing to molecular recognition: prediction and discovery of a binding site on the surface of polo-like kinase 1
Resolution
1.4 Å
Binding residue
(original residue number in PDB)
W414 D416 Y485 H489 L490 L491 R516 F535 H538 K540
Binding residue
(residue number reindexed from 1)
W52 D54 Y123 H127 L128 L129 R154 F173 H176 K178
Enzymatic activity
Enzyme Commision number
2.7.11.21
: polo kinase.
External links
PDB
RCSB:3p34
,
PDBe:3p34
,
PDBj:3p34
PDBsum
3p34
PubMed
21472932
UniProt
P53350
|PLK1_HUMAN Serine/threonine-protein kinase PLK1 (Gene Name=PLK1)
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