Structure of PDB 3p2z Chain A Binding Site BS01
Receptor Information
>3p2z Chain A (length=210) Species:
9606
(Homo sapiens) [
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SPEFDCHLSDMLQQLHSVEAEDPACIPIFWVSKWVDYSDKYGLGYQLCDN
SVGVLFNDSTRLILYNDGDSLQYIERDGTESYLTVSSHPNSLMKKITLLK
YFRNYMSEHLLKAGANITPDELARLPYLRTWFRTRSAIILHLSNGSVQIN
FFQDHTKLILCPLMAAVTYIDEKRDFRTYRLSLLEEYGCCKELASRLRYA
RTMVDKLLSS
Ligand information
>3p2z Chain B (length=6) [
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PLHSTA
Receptor-Ligand Complex Structure
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PDB
3p2z
From crystal packing to molecular recognition: prediction and discovery of a binding site on the surface of polo-like kinase 1
Resolution
1.79 Å
Binding residue
(original residue number in PDB)
W414 V415 D416 H489 L490 L491 R516 F535 H538 K540
Binding residue
(residue number reindexed from 1)
W34 V35 D36 H109 L110 L111 R133 F152 H155 K157
Enzymatic activity
Enzyme Commision number
2.7.11.21
: polo kinase.
External links
PDB
RCSB:3p2z
,
PDBe:3p2z
,
PDBj:3p2z
PDBsum
3p2z
PubMed
21472932
UniProt
P53350
|PLK1_HUMAN Serine/threonine-protein kinase PLK1 (Gene Name=PLK1)
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