Structure of PDB 3opx Chain A Binding Site BS01

Receptor Information
>3opx Chain A (length=247) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
HLESLTHPGSKVTFPIDTPQNPNLKVFFFAIDNCLYKSSTRIHDLMQQSI
LRFFQTHLKLSPEDAHVLNNSYYKEYGLAIRGLVMFHKVNALEYNRLVDD
SLPLQDILKPDIPLRNMLLRLRQSGKIDKLWLFTNAYKNHAIRCLRLLGI
ADLFDGLTYCDYSRTDTLVCKPHVKAFEKAMKESGLARYENAYFIDDSGK
NIETGIKLGMKTCIHLVENEVNQTPEGAIVISDILELPHVVSDLFLE
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain3opx Chain A Residue 264 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB3opx Crystal structure of pyrimidine 5 -nucleotidase SDT1 from Saccharomyces cerevisiae complexed with uridine 5'-monophosphate
Resolution1.7 Å
Binding residue
(original residue number in PDB)		D38 D203
Binding residue
(residue number reindexed from 1)		D32 D197
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0008252 nucleotidase activity
GO:0016787 hydrolase activity
Biological Process
GO:0006206 pyrimidine nucleobase metabolic process
GO:0009166 nucleotide catabolic process
Cellular Component
GO:0005575 cellular_component

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:3opx, PDBe:3opx, PDBj:3opx
PDBsum3opx
PubMed
UniProtP53078|SDT1_YEAST Suppressor of disruption of TFIIS (Gene Name=SDT1)

[Back to BioLiP]