Structure of PDB 3olp Chain A Binding Site BS01

Receptor Information
>3olp Chain A (length=543) Species: 90371 (Salmonella enterica subsp. enterica serovar Typhimurium) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
AIHNRAGQPAQQSDLINVAQLTAQYYVLKPEAGNAEHAVKFGTSGHRGSA
GRHSFNEPHILAIAQAIAEERAKNGITGPCYVGKDTHALSEPAFISVLEV
LAANGVDVIVQENNGFTPTPAVSNAILVHNKKGGPLADGIVITPSHNPPE
DGGIKYNPPNGGPADTNVTKVVEDRANALLAGGLQGVKRISLDAAMASGH
VKAVDLVQPFVEGLADIVDMAAIQKAGLTLGVDPLGGSGIEYWKRIAEHY
KLNLTLVNDQVDQTFRFMHLDKDGAIRMDCSSECAMAGLLALRDKFDLAF
ANDPDYDRHGIVTPAGLMNPNHYLAVAINYLFQHRPLWGKDVAVGKTLVS
SAMIDRVVNDLGRKLVEVPVGFKWFVDGLFDGSFGFGGEESAGASFLRFD
GTPWSTDKDGIIMCLLAAEITAVTGKNPQEHYNELAARFGAPSYNRLQAS
ATSAQKAALSKLSPEMVSASTLAGDPITARLTAAPGNGASIGGLKVMTDN
GWFAARPSGTEDAYKIYCESFLGEEHRKQIEKEAVEIVSEVLK
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain3olp Chain A Residue 547 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB3olp Crystal structure of a bacterial phosphoglucomutase, an enzyme involved in the virulence of multiple human pathogens.
Resolution1.95 Å
Binding residue
(original residue number in PDB)		S146 D304 D306 D308
Binding residue
(residue number reindexed from 1)		S145 D303 D305 D307
Annotation score1
Enzymatic activity
Catalytic site (original residue number in PDB) S146 H147 D304 D306 D308 R309 K409
Catalytic site (residue number reindexed from 1) S145 H146 D303 D305 D307 R308 K408
Enzyme Commision number 5.4.2.2: phosphoglucomutase (alpha-D-glucose-1,6-bisphosphate-dependent).
Gene Ontology
Molecular Function
GO:0000287 magnesium ion binding
GO:0004614 phosphoglucomutase activity
GO:0016853 isomerase activity
GO:0016868 intramolecular phosphotransferase activity
GO:0046872 metal ion binding
Biological Process
GO:0005975 carbohydrate metabolic process
Cellular Component
GO:0005829 cytosol

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:3olp, PDBe:3olp, PDBj:3olp
PDBsum3olp
PubMed21246636
UniProtQ8ZQW9

[Back to BioLiP]