Structure of PDB 3ohb Chain A Binding Site BS01

Receptor Information
>3ohb Chain A (length=515) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
DPHMSKFTWKELIQLGSPSKAYESSLACIAHIDMNAFFAQVEQMRCGLSK
EDPVVCVQWNSIIAVSYAARKYGISRMDTIQEALKKCSNLIPIHTAVFKK
GEDFWQYHDGCGSWVQDPAKQISVEDHKVSLEPYRRESRKALAIFKWACD
LVERASIDEVFLDLGRICFNMLMFDNEYELTGDLKLKDALSNIREAFIGG
NYDINSHLPLIPEKIKSLKFEGDVFNPEGRDLITDWDDVILALGSQVCKG
IRDSIKDILGYTTSCGLSSTKNVCKLASNYKKPDAQTIVKNDCLLDFLDC
GKFEITSFWTLGGVLGKELIDVLDLPHENSIKHIRETWPDNAGQLKEFLD
AKVKQSDYDRSTSNIDPLKTADLAEKLFKLSRGRYGLPLSSRPVVKSMMS
NKNLRGKSCNSIVDCISWLEVFCAELTSRIQDLEQEYNKIVIPRTVSISL
KTKSYEVYRKSGPVAYKGINFQSHELLKVGIKFVTDLDIKGKNKSYYPLT
KLSMTITNFDIIDLQ
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB3ohb Structural basis for error-free replication of oxidatively damaged DNA by yeast DNA polymerase eta.
Resolution2.0 Å
Binding residue
(original residue number in PDB)
Q55 W56 R73 M74 K125 V126 R132 K393 M395 M396 S397 N398 N400 R426
Binding residue
(residue number reindexed from 1)
Q58 W59 R76 M77 K128 V129 R135 K396 M398 M399 S400 N401 N403 R429
Enzymatic activity
Enzyme Commision number 2.7.7.7: DNA-directed DNA polymerase.
Gene Ontology
Molecular Function
GO:0003684 damaged DNA binding
Biological Process
GO:0006281 DNA repair

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Molecular Function

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Biological Process
External links
PDB RCSB:3ohb, PDBe:3ohb, PDBj:3ohb
PDBsum3ohb
PubMed21070945
UniProtQ04049|POLH_YEAST DNA polymerase eta (Gene Name=RAD30)

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