Structure of PDB 3og8 Chain A Binding Site BS01
Receptor Information
>3og8 Chain A (length=126) Species:
9606
(Homo sapiens) [
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KENKKLLCRKCKALACYTADVRVIEESHYTVLGDAFKECFVSRPHPKPKQ
FSSFEKRAKIFCARQNCSHDWGIHVKYKTFEIPVIKIESFVVEDIATGVQ
TLYSKWKDFHFEKIPFDPAEMSKLEH
Ligand information
>3og8 Chain C (length=14) [
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ggcgcgcgcgcgcc
..............
Receptor-Ligand Complex Structure
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PDB
3og8
Crystal structure of RIG-I C-terminal domain bound to blunt-ended double-strand RNA without 5' triphosphate.
Resolution
2.4 Å
Binding residue
(original residue number in PDB)
H830 F853 K858 G874 I875 V886 K888 K907 W908
Binding residue
(residue number reindexed from 1)
H28 F51 K56 G72 I73 V84 K86 K105 W106
Enzymatic activity
Enzyme Commision number
3.6.4.13
: RNA helicase.
External links
PDB
RCSB:3og8
,
PDBe:3og8
,
PDBj:3og8
PDBsum
3og8
PubMed
20961956
UniProt
O95786
|RIGI_HUMAN Antiviral innate immune response receptor RIG-I (Gene Name=RIGI)
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