Structure of PDB 3oes Chain A Binding Site BS01

Receptor Information

>3oes Chain A (length=157) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

RYRKVVILGYRCVGKTSLAHQFVEGEFSEGYDPTVENTYSKIVTEFHLHL
VDTAGQDEYSILPYSFIIGVHGYVLVYSVTSLHSFQVIESLYQKLHERVP
VVLVGNKADLSPEREVQAVEGKKLAESWGATFMESSARENQLTQGIFTKV
IQEIARV

Ligand information

Ligand ID

InChI

InChI=1S/Mg/q+2

InChIKey

JLVVSXFLKOJNIY-UHFFFAOYSA-N

SMILES

Software	SMILES
ACDLabs 10.04 OpenEye OEToolkits 1.5.0	[Mg+2]
CACTVS 3.341	[Mg++]

Formula

Name

MAGNESIUM ION

PDB chain

3oes Chain A Residue 202 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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Structure summary

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PDB	3oes Crystal structure of the small GTPase RhebL1
Resolution	2.301 Å
Binding residue (original residue number in PDB)	T20 T38
Binding residue (residue number reindexed from 1)	T16 T34
Annotation score	1

Enzymatic activity

Enzyme Commision number

Gene Ontology

	Molecular Function
GO:0003924	GTPase activity
GO:0005515	protein binding
GO:0005525	GTP binding
GO:0016787	hydrolase activity
GO:0019003	GDP binding
GO:0046872	metal ion binding

	Biological Process
GO:0007165	signal transduction
GO:0007264	small GTPase-mediated signal transduction
GO:0031929	TOR signaling
GO:0051092	positive regulation of NF-kappaB transcription factor activity

	Cellular Component
GO:0005737	cytoplasm
GO:0005886	plasma membrane
GO:0012505	endomembrane system
GO:0016020	membrane

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Cellular Component

External links

PDB	RCSB:3oes, PDBe:3oes, PDBj:3oes
PDBsum	3oes
PubMed
UniProt	Q8TAI7\|REBL1_HUMAN GTPase RhebL1 (Gene Name=RHEBL1)

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