Structure of PDB 3o5t Chain A Binding Site BS01

Receptor Information

>3o5t Chain A (length=295) Species: 192 (Azospirillum brasilense)

DHSIRSRALGAYLGLACGDALGATVEFLTKGEIAHQYGVHKHIKGGGWLK
LPAGQVTDDTEMSIHLGRAILAAPEWDARRAAEEFAVWLKGVPVDVGDTT
RRGIRRFIMHGTLSEPESEYHAGNGAAMRNLPVALATLGDDAAFERWTVE
QAHITHCNAMSDAATLTLGHMVRRLVLGGDVRDVRDESNKLIAKHRQFKF
QPYRGLATAYIVDTMQTVMHYYFQTDSVESCVVETVNQGGDADTTGAIAG
MLAGATYGVETIPPRWLRKLDRDVYNEICAQVDGLLARAPALKQG

Ligand information

• Ligand ID: MG
• InChI: InChI=1S/Mg/q+2
• InChIKey: JLVVSXFLKOJNIY-UHFFFAOYSA-N
• SMILES:
  ACDLabs 10.04
  OpenEye OEToolkits 1.5.0: [Mg+2]
  CACTVS 3.341: [Mg++]
• Formula: Mg
• Name: MAGNESIUM ION
• DrugBank: DB01378
• PDB chain: 3o5t Chain A Residue 298

Receptor-Ligand Complex Structure

Structure summary

• PDB: 3o5t Crystal structure of the GlnZ-DraG complex reveals a different form of PII-target interaction
• Resolution: 2.09 Å
• Binding residue (original residue number in PDB): E28 D243 D245 T246
• Binding residue (residue number reindexed from 1): E26 D241 D243 T244
• Annotation score: 1

Enzymatic activity

• Enzyme Commision number: 3.2.2.24: ADP-ribosyl-[dinitrogen reductase] hydrolase.

Gene Ontology

Molecular Function

• GO:0000166 nucleotide binding
• GO:0016798 hydrolase activity, acting on glycosyl bonds
• GO:0046872 metal ion binding
• GO:0047407 ADP-ribosyl-[dinitrogen reductase] hydrolase activity

External links

• PDB: RCSB:3o5t, PDBe:3o5t, PDBj:3o5t
• PDBsum: 3o5t
• PubMed: 22074780
• UniProt: A7XNI2