Structure of PDB 3o4n Chain A Binding Site BS01
Receptor Information
>3o4n Chain A (length=133) Species:
11886
(Rous sarcoma virus) [
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QIWQTDFTLEPRMAPRSWLAVTVDTASSAIVVTQHGRVTSVAAQHHWATA
IAVLGRPKAIKTDNGSCFTSKSTREWLARWGIAHTTQAMVERANRLLKDK
IRVLAEGDGFMKRIPASKQGELLAKAMYALNHF
Ligand information
Ligand ID
ZN
InChI
InChI=1S/Zn/q+2
InChIKey
PTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
Software
SMILES
CACTVS 3.341
[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0
[Zn+2]
Formula
Zn
Name
ZINC ION
ChEMBL
CHEMBL1236970
DrugBank
DB14532
ZINC
PDB chain
3o4n Chain A Residue 2001 [
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Receptor-Ligand Complex Structure
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PDB
3o4n
A crystal structure of the catalytic core domain of an avian sarcoma and leukemia virus integrase suggests an alternate dimeric assembly.
Resolution
1.8 Å
Binding residue
(original residue number in PDB)
D64 D121
Binding residue
(residue number reindexed from 1)
D6 D63
Annotation score
1
Enzymatic activity
Enzyme Commision number
2.7.7.-
2.7.7.49
: RNA-directed DNA polymerase.
2.7.7.7
: DNA-directed DNA polymerase.
3.1.-.-
3.1.26.4
: ribonuclease H.
3.4.23.-
Gene Ontology
Molecular Function
GO:0003676
nucleic acid binding
Biological Process
GO:0015074
DNA integration
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Molecular Function
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Biological Process
External links
PDB
RCSB:3o4n
,
PDBe:3o4n
,
PDBj:3o4n
PDBsum
3o4n
PubMed
21857987
UniProt
O92956
|POL_RSVSB Gag-Pol polyprotein (Gene Name=gag-pol)
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