Structure of PDB 3o3e Chain A Binding Site BS01
Receptor Information
>3o3e Chain A (length=275) Species:
9606
(Homo sapiens) [
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GSHSMRYFFTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDAASQRMEPRAP
WIEQEGPEYWDGETRKVKAHSQTHRVDLGTLRGYYNQSEAGSHTVQRMYG
CDVGSDWRFLRGYHQYAYDGKDYIALKEDLRSWTAADMAAQTTKHKWEAA
HVAEQLRAYLEGTCVEWLRRYLENGKETLQRTDAPKTHMTHHAVSDHEAT
LRCWALSFYPAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVP
SGQEQRYTCHVQHEGLPKPLTLRWE
Ligand information
>3o3e Chain C (length=8) [
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ALAWGLTV
Receptor-Ligand Complex Structure
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PDB
3o3e
Crystal structures of HLA-A*0201 complexed with Melan-A/MART-1(26(27L)-35) peptidomimetics reveal conformational heterogeneity and highlight degeneracy of T cell recognition.
Resolution
1.85 Å
Binding residue
(original residue number in PDB)
Y7 E63 K66 V67 T73 D77 Y84 Y99 T143 W147 V152 Q155 L156 Y159 W167
Binding residue
(residue number reindexed from 1)
Y7 E63 K66 V67 T73 D77 Y84 Y99 T143 W147 V152 Q155 L156 Y159 W167
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:3o3e
,
PDBe:3o3e
,
PDBj:3o3e
PDBsum
3o3e
PubMed
20806940
UniProt
P04439
|HLAA_HUMAN HLA class I histocompatibility antigen, A alpha chain (Gene Name=HLA-A)
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