Structure of PDB 3o36 Chain A Binding Site BS01
Receptor Information
>3o36 Chain A (length=184) Species:
9606
(Homo sapiens) [
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SPNEDWCAVCQNGGELLCCEKCPKVFHLSCHVPTLTNFPSGEWICTFCRD
LSKPEVEYDCDAPSHNSEKKKTEGLVKLTPIDKRKCERLLLFLYCHEMSL
AFQDPVPLTVPDYYKIIKNPMDLSTIKKRLQEDYSMYSKPEDFVADFRLI
FQNCAEFNEPDSEVANAGIKLENYFEELLKNLYP
Ligand information
>3o36 Chain E (length=3) Species:
9606
(Homo sapiens) [
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GAK
Receptor-Ligand Complex Structure
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PDB
3o36
TRIM24 links a non-canonical histone signature to breast cancer.
Resolution
1.7 Å
Binding residue
(original residue number in PDB)
V928 F979 N980 E981
Binding residue
(residue number reindexed from 1)
V106 F157 N158 E159
Enzymatic activity
Enzyme Commision number
2.3.2.27
: RING-type E3 ubiquitin transferase.
External links
PDB
RCSB:3o36
,
PDBe:3o36
,
PDBj:3o36
PDBsum
3o36
PubMed
21164480
UniProt
O15164
|TIF1A_HUMAN Transcription intermediary factor 1-alpha (Gene Name=TRIM24)
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