Structure of PDB 3o35 Chain A Binding Site BS01
Receptor Information
>3o35 Chain A (length=178) Species:
9606
(Homo sapiens) [
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PNEDWCAVCQNGGELLCCEKCPKVFHLSCHVPTLTNFPSGEWICTFCRDL
SKPEVEYDCDAEKKKTEGLVKLTPIDKRKCERLLLFLYCHEMSLAFQDPV
PLTVPDYYKIIKNPMDLSTIKKRLQEDYSMYSKPEDFVADFRLIFQNCAE
FNEPDSEVANAGIKLENYFEELLKNLYP
Ligand information
>3o35 Chain E (length=5) Species:
9606
(Homo sapiens) [
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ARKSA
Receptor-Ligand Complex Structure
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PDB
3o35
TRIM24 links a non-canonical histone signature to breast cancer.
Resolution
1.76 Å
Binding residue
(original residue number in PDB)
F924 V928 P933 N980
Binding residue
(residue number reindexed from 1)
F96 V100 P105 N152
Enzymatic activity
Enzyme Commision number
2.3.2.27
: RING-type E3 ubiquitin transferase.
External links
PDB
RCSB:3o35
,
PDBe:3o35
,
PDBj:3o35
PDBsum
3o35
PubMed
21164480
UniProt
O15164
|TIF1A_HUMAN Transcription intermediary factor 1-alpha (Gene Name=TRIM24)
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